- Cardiology/Surgery/Basic science and research
-
The Complexities of Intravenous Fluid Research: Questions of Scale, Volume, and Accumulation
-
Neil J Glassford, Rinaldo Bellomo
-
Korean J Crit Care Med. 2016;31(4):276-299. Published online November 30, 2016
-
DOI: https://doi.org/10.4266/kjccm.2016.00934
-
-
19,202
View
-
569
Download
-
14
Crossref
-
Abstract
PDF
- Despite near ubiquity, information regarding fluids consumption at a health care systems level, and patient exposure at an individual level, is surprisingly limited in the medical literature. The epidemiology of the foundational medical intervention of intravenous fluid administration is incredibly complex, with millions of patients being exposed internationally every year. Fluid is being given for different reasons, to different targets, following different triggers, by different specialties in different countries, and any observations that can be made are thought to have limited external validity to other jurisdictions and patient groups. The independent effects of fluid administration and fluid accumulation are very hard to separate from other markers of illness severity and aspects of the process of care. Fluid accumulation can result in organ injury, even when the fluid is being given to purportedly ameliorate or prevent such injury, and if it were independently associated with mortality then would be an easily accessible and modifiable risk factor for subsequent morbidity or death. Despite their ubiquity, it is clear that we have limited understanding of the effects of the intravenous fluids we use daily in the most vulnerable of patient groups. The research agenda in this field is large and urgent.
-
Citations
Citations to this article as recorded by
- Closed-Loop Control of Fluid Resuscitation Using Reinforcement Learning
Elham Estiri, Hossein Mirinejad IEEE Access.2023; 11: 140569. CrossRef - Fluid Stewardship of Maintenance Intravenous Fluids
John R. Carr, W. Anthony Hawkins, Andrea Sikora Newsome, Susan E. Smith, Clemmons Amber B, Christopher M. Bland, Trisha N. Branan Journal of Pharmacy Practice.2022; 35(5): 769. CrossRef - Clinician attitudes and concordance with self-assessed and actual intravenous fluid prescribing patterns: A single-institution evaluation of survey and electronic prescribing data
Michelle C. Spiegel, Annie N. Simpson, Nandita R. Nadig, Dee W. Ford, Andrew J. Goodwin The American Journal of the Medical Sciences.2022; 364(1): 36. CrossRef - Acetate‐ versus lactate‐buffered crystalloid solutions: A systematic review with meta‐analysis and trial sequential analysis
Karen Louise Ellekjaer, Anders Perner, Praleene Sivapalan, Morten Hylander Møller Acta Anaesthesiologica Scandinavica.2022; 66(7): 782. CrossRef - A fuzzy model for predicting burn patients’ intravenous fluid resuscitation rate
Sayma Alam Suha, M. Akhtaruzzaman, Tahsina Farah Sanam Healthcare Analytics.2022; 2: 100070. CrossRef - Development and implementation of a clinical decision support-based initiative to drive intravenous fluid prescribing
Michelle C. Spiegel, Annie N. Simpson, Achsah Philip, Carolyn M. Bell, Nandita R. Nadig, Dee W. Ford, Andrew J. Goodwin International Journal of Medical Informatics.2021; 156: 104619. CrossRef - Influence of acetate containing fluid versus lactate containing fluid on acid-base status, electrolyte level, and blood lactate level in dehydrated dogs
Annika Heitland, Ute Klein-Richers, Katrin Hartmann, René Dörfelt Veterinary World.2021; : 2714. CrossRef - Infusion fluids: a clinical pharmacologist’s view
E.A. Ushkalova, S.K. Zyryanov, K.E. Zatolochina, O.I. Butranova Anesteziologiya i reanimatologiya.2021; (6): 100. CrossRef - Pathophysiology of Volume Administration in Septic Shock and the Role of the Clinical Pharmacist
Brittany D. Bissell, Breanne Mefford Annals of Pharmacotherapy.2020; 54(4): 388. CrossRef - Lactate versus acetate buffered intravenous crystalloid solutions: a scoping review
Karen L. Ellekjaer, Anders Perner, Martine M. Jensen, Morten H. Møller British Journal of Anaesthesia.2020; 125(5): 693. CrossRef - Balanced Crystalloid Solutions
Matthew W. Semler, John A. Kellum American Journal of Respiratory and Critical Care Medicine.2019; 199(8): 952. CrossRef - Does Fluid Type and Amount Affect Kidney Function in Critical Illness?
Neil J. Glassford, Rinaldo Bellomo Critical Care Clinics.2018; 34(2): 279. CrossRef - Resuscitation fluids
Jonathan D. Casey, Ryan M. Brown, Matthew W. Semler Current Opinion in Critical Care.2018; 24(6): 512. CrossRef - Utility of Volume Assessment Using Bioelectrical Impedance Analysis in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Prospective Observational Study
Ki Hyun Park, Jung-ho Shin, Jin Ho Hwang, Su Hyun Kim The Korean Journal of Critical Care Medicine.2017; 32(3): 256. CrossRef
|